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[Ectogenous fragile histidine triad gene inhibits the malignant phenotype of human lung cancer cell line A549 in vitro and in vivo].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 May 2005

Zhang Li-qun, Wang Hui, Lai Bai-tang, Yue Wen-tao, Zhan Xiu-ping, Yang Xue-hui, Zhang Chun-yan, Zhang Tong-mei

Abstract excerpt

OBJECTIVE: To investigate the inhibition effects of fragile histidine triad (FHIT) gene on the malignant growth of A549 cell line. METHODS: A mammalian expression vector PEGFP-FHIT was constructed and transfected into the A549 cell line by lipofectamine. Then the transfected cell line was screened by G418. Individual G418-resistant colonies were isolated by limited dilution. The monoclonal transfected cell line...

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Identifiers

PMID: 15949315

Genes

FHIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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