Article
Kinetics of error generation in homologous B-family DNA polymerases.
Nucleic acids research - 1 Jan 2006
Hogg Matthew, Cooper Wendy, Reha-Krantz Linda, Wallace Susan S
Abstract excerpt
The kinetics of forming a proper Watson-Crick base pair as well incorporating bases opposite furan, an abasic site analog, have been well characterized for the B Family replicative DNA polymerase from bacteriophage T4. Structural studies of these reactions, however, have only been performed with the homologous enzyme from bacteriophage RB69. In this work, the homologous enzymes from RB69 and T4 were compared in...
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