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Article

PCR performance of the B-type DNA polymerase from the thermophilic euryarchaeon Thermococcus aggregans improved by mutations in the Y-GG/A motif.

Nucleic acids research - 15 Oct 2000

Böhlke K, Pisani F M, Vorgias C E, Frey B, Sobek H, Rossi M, Antranikian G

Abstract excerpt

The effect of mutations in the highly conserved Y-GG/A motif of B-type DNA polymerases was studied in the DNA polymerase from the hyperthermophilic euryarchaeon Thermococcus aggregans. This motif plays a critical role in the balance between the synthesis and degradation of the DNA chain. Five dif...

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Identifiers

PMID: 11024170
DOI: 10.1093/nar/28.20.3910
PMCID: PMC110800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11024170-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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