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Article

Role of histone deacetylase Rpd3 in regulating rRNA gene transcription and nucleolar structure in yeast.

Molecular and cellular biology - 1 May 2006

Oakes Melanie L, Siddiqi Imran, French Sarah L, Vu Loan, Sato Manabu, Aris John P, Beyer Ann L, Nomura Masayasu

Abstract excerpt

The 35S rRNA genes at the RDN1 locus in Saccharomyces cerevisiae can be transcribed by RNA polymerase (Pol) II in addition to Pol I, but Pol II transcription is usually silenced. The deletion of RRN9 encoding an essential subunit of the Pol I transcription factor, upstream activation factor, is known to abolish Pol I transcription and derepress Pol II transcription of rRNA genes, giving rise to polymerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16648483
DOI: 10.1128/MCB.26.10.3889-3901.2006
PMCID: PMC1489006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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