Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.

Cell - 18 Nov 2005

Carrozza Michael J, Li Bing, Florens Laurence, Suganuma Tamaki, Swanson Selene K, Lee Kenneth K, Shia Wei-Jong, Anderson Scott, Yates John, Washburn Michael P, Workman Jerry L

Abstract excerpt

Yeast Rpd3 histone deacetylase plays an important role at actively transcribed genes. We characterized two distinct Rpd3 complexes, Rpd3L and Rpd3S, by MudPIT analysis. Both complexes shared a three subunit core and Rpd3L contains unique subunits consistent with being a promoter targeted corepressor. Rco1 and Eaf3 were subunits specific to Rpd3S. Mutants of RCO1 and EAF3 exhibited increased acetylation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Molecular Weight
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Open Reading Frames

Share to Promoter Regions, Genetic

Share to Protein Binding

Share to Repressor Proteins

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 16286007
DOI: 10.1016/j.cell.2005.10.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.PMID 16286007Read ↗

Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.Semantic proximity Read ↗

DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes.Semantic proximity Read ↗

Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes.Semantic proximity Read ↗

SAGA and Rpd3 chromatin modification complexes dynamically regulate heat shock gene structure and expression.Semantic proximity Read ↗

Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo.Semantic proximity Read ↗

The conserved histone deacetylase Rpd3 and its DNA binding subunit Ume6 control dynamic transcript architecture during mitotic growth and meiotic development.Semantic proximity Read ↗

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.Semantic proximity Read ↗

The histone deacetylase Rpd3/Sin3/Ume6 complex represses an acetate-inducible isoform of VTH2 in fermenting budding yeast cells.Semantic proximity Read ↗

Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription.Semantic proximity Read ↗

Genome-wide binding map of the histone deacetylase Rpd3 in yeast.Semantic proximity Read ↗

Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression.Semantic proximity Read ↗

Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.