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Article

Delayed rRNA processing results in significant ribosome biogenesis and functional defects.

Molecular and cellular biology - 1 Mar 2003

Meskauskas Arturas, Baxter Jennifer L, Carr Edward A, Yasenchak Jason, Gallagher Jennifer E G, Baserga Susan J, Dinman Jonathan D

Abstract excerpt

mof6-1 was originally isolated as a recessive mutation in Saccharomyces cerevisiae which promoted increased efficiencies of programmed -1 ribosomal frameshifting and rendered cells unable to maintain the killer virus. Here, we demonstrate that mof6-1 is a unique allele of the histone deacetylase RPD3, that the deacetylase function of Rpd3p is required for controlling wild-type levels of frameshifting and virus...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12588980
DOI: 10.1128/MCB.23.5.1602-1613.2003
PMCID: PMC151716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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