Article
Reduced expression of beta-catenin inhibitor Chibby in colon carcinoma cell lines.
World journal of gastroenterology - 14 Mar 2006
Schuierer Marion M, Graf Elisabeth, Takemaru Ken-Ichi, Dietmaier Wolfgang, Bosserhoff Anja-Katrin
Abstract excerpt
AIM: To analyse the Chibby expression and its function in colon carcinoma cell lines and colorectal carcinoma (CRC). METHODS: Chibby expression levels were investigated by quantitative RT-PCR in a panel of seven different colon carcinoma cell lines. By sequencing, we analysed mutational status of Chibby. To test whether Chibby exhibited effects on beta-catenin signalling in colon carcinoma cells, we transfected...
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