Article
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Gastroenterology - 1 Jul 2009
Fritzmann Johannes, Morkel Markus, Besser Daniel, Budczies Jan, Kosel Frauke, Brembeck Felix H, Stein Ulrike, Fichtner Iduna, Schlag Peter M, Birchmeier Walter
Abstract excerpt
BACKGROUND & AIMS: Much is known about the genes and mutations that cause colorectal cancer (CRC), yet only a few have been associated with CRC metastasis. We performed expression-profiling experiments to identify genetic markers of risk and to elucidate the molecular mechanisms of CRC metastasis. METHODS: We compared gene expression patterns between metastatic and nonmetastatic stage-matched human colorectal...
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