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Article

Stu2p binds tubulin and undergoes an open-to-closed conformational change.

The Journal of cell biology - 27 Mar 2006

Al-Bassam Jawdat, van Breugel Mark, Harrison Stephen C, Hyman Anthony

Abstract excerpt

Stu2p from budding yeast belongs to the conserved Dis1/XMAP215 family of microtubule-associated proteins (MAPs). The common feature of proteins in this family is the presence of HEAT repeat-containing TOG domains near the NH2 terminus. We have investigated the functions of the two TOG domains of Stu2p in vivo and in vitro. Our data suggest that Stu2p regulates microtubule dynamics through two separate activities....

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Identifiers

PMID: 16567500
DOI: 10.1083/jcb.200511010
PMCID: PMC2063759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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