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Article

Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity.

The Journal of cell biology - 6 Oct 2025

Abouelghar Ahmed A, Carrier Joseph S, Torvi Julia R, Jenson Erin, Jones Chloe, Gangadharan Binnu, Prinslow Elisabeth G, Rice Luke M, Lagesse Brent, Barnes Georjana, Miller Matthew P

Abstract excerpt

ch-TOG family proteins, including the budding yeast Stu2, are essential for spindle formation and chromosome segregation. Such functions depend on an array of activities ranging from microtubule nucleation, polymerization, and depolymerization to conferring tension sensitivity to kinetochores. This functional diversity makes it challenging to dissect these various functions and understand their relative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40899992
DOI: 10.1083/jcb.202209025
PMCID: PMC12452106

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Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity.PMID 40899992Read ↗

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