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Article

Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body.

The Journal of cell biology - 1 Dec 1997

Wang P J, Huffaker T C

Abstract excerpt

Previously we isolated tub2-423, a cold-sensitive allele of the Saccharomyces cerevisiae gene encoding beta-tubulin that confers a defect in mitotic spindle function. In an attempt to identify additional proteins that are important for spindle function, we screened for suppressors of the cold sensitivity of tub2-423 and obtained two alleles of a novel gene, STU2. STU2 is an essential gene and encodes a protein...

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Identifiers

PMID: 9382872
DOI: 10.1083/jcb.139.5.1271
PMCID: PMC2140218

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Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body.PMID 9382872Read ↗

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Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast.Semantic proximity Read ↗

Spc24 and Stu2 promote spindle integrity when DNA replication is stalled.Semantic proximity Read ↗

Stu1p is physically associated with beta-tubulin and is required for structural integrity of the mitotic spindle.Semantic proximity Read ↗

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Structural basis of Stu2 recruitment to yeast kinetochores.Semantic proximity Read ↗

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Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity.Semantic proximity Read ↗

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