Article
The interaction of TOGp with microtubules and tubulin.
The Journal of biological chemistry - 7 Jul 2000
Spittle C, Charrasse S, Larroque C, Cassimeris L
Abstract excerpt
TOGp is the human homolog of XMAP215, a Xenopus microtubule-associated protein that promotes rapid microtubule assembly at plus ends. These proteins are thought to be critical for microtubule assembly and/or mitotic spindle formation. To understand how TOGp interacts with the microtubule lattice, we cloned full-length TOGp and various truncations for expression in a reticulocyte lysate system. Based on...
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