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Article

Use of phenotypic covariates in association analysis by sequential addition of cases.

European journal of human genetics : EJHG - 1 May 2006

Macgregor Stuart, Craddock Nick, Holmans Peter A

Abstract excerpt

Optimal use of phenotype information is important in complex disease gene mapping. We describe a method, sequential addition, for the analysis of case-control data by taking into account of a quantitative trait that is measured in cases but not in controls. The method also provides an estimate of the best phenotype definition for future studies. We demonstrate proof of principle, using an example of incorporation...

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Source

Identifiers

PMID: 16538225
DOI: 10.1038/sj.ejhg.5201604

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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