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Article

A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype.

American journal of human genetics - 1 Aug 1990

Amos C I, Elston R C, Bonney G E, Keats B J, Berenson G S

Abstract excerpt

The robust or model-free method for detecting linkage developed by Haseman and Elston for data from sib pairs is extended to incorporate observations of multiple traits on each individual. A method is proposed that estimates the linear function that results in the strongest correlation between the squared pair differences in the trait measurements and identity by descent at a marker locus. The method is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 2378349
PMCID: PMC1683708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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