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Article

Regression models for allele sharing: analysis of accumulating data in affected sib pair studies.

Statistics in medicine - 15 Feb 2002

Bull Shelley B, Greenwood Celia M T, Mirea Lucia, Morgan Kenneth

Abstract excerpt

Advances in human genome mapping have led to the identification of large numbers of genetic markers that allow systematic searches for multiple disease susceptibility genes for complex traits. A common design involves the recruitment of families with at least two children affected with the disease of interest. The objective is to find chromosomal regions that harbour susceptibility genes for the disease. The...

Topics

Adolescent
Algorithms
Alleles
Chromosome Mapping
DNA
Genetic Linkage
Genetic Predisposition to Disease
Genotype
Humans
Inflammatory Bowel Diseases
Jews
Lod Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

Nuclear Family

Ontario

Regression Analysis

Source

Identifiers

PMID: 11813229
DOI: 10.1002/sim.1028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-11813229-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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