Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ordered-subset analysis (OSA) for family-based association mapping of complex traits.

Genetic epidemiology - 1 Nov 2008

Chung Ren-Hua, Schmidt Silke, Martin Eden R, Hauser Elizabeth R

Abstract excerpt

Association analysis provides a powerful tool for complex disease gene mapping. However, in the presence of genetic heterogeneity, the power for association analysis can be low since only a fraction of the collected families may carry a specific disease susceptibility allele. Ordered-subset analysis (OSA) is a linkage test that can be powerful in the presence of genetic heterogeneity. OSA uses trait-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Computer Simulation
Share to Genes, Recessive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Macular Degeneration

Share to Models, Statistical

Share to Reproducibility of Results

Share to Research Design

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 18473393
DOI: 10.1002/gepi.20340
PMCID: PMC2582061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ordered-subset analysis (OSA) for family-based association mapping of complex traits.PMID 18473393Read ↗

Ordered subset analysis for case-control studies.Semantic proximity Read ↗

Ordered subset analysis in genetic linkage mapping of complex traits.Semantic proximity Read ↗

Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12.Semantic proximity Read ↗

Interpreting analyses of continuous covariates in affected sibling pair linkage studies.Semantic proximity Read ↗

Ordered subset analysis identifies loci influencing lung cancer risk on chromosomes 6q and 12q.Semantic proximity Read ↗

Increased efficiency of case-control association analysis by using allele-sharing and covariate information.Semantic proximity Read ↗

Early adult-onset POAG linked to 15q11-13 using ordered subset analysis.Semantic proximity Read ↗

Family-based association test using both common and rare variants and accounting for directions of effects for sequencing data.Semantic proximity Read ↗

Application of an ordered subset analysis approach to the genetics of alcoholism.Semantic proximity Read ↗

A latent class model for testing for linkage and classifying families when the sample may contain segregating and non-segregating families.Semantic proximity Read ↗

Genetic association mapping based on discordant sib pairs: the discordant-alleles test.Semantic proximity Read ↗

Ordered subset analysis of copy number variation association with age at onset of Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.