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Article

Extensions to sib-pair linkage tests applicable to disorders characterized by delayed onset.

Genetic epidemiology - 1 Jan 1990

Dawson D V, Kaplan E B, Elston R C

Abstract excerpt

Extensions of the approach to sib-pair linkage tests developed by Haseman and Elston [Behav Genet 2:3-19, 1972] are proposed which incorporate information on age of onset and age at examination. Alternate sources for the age of onset corrections are described, including models for the estimation of parameters associated with the age of onset distribution. Simulation is used to examine the performance of the...

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PMID: 2292370
DOI: 10.1002/gepi.1370070607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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