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Article

Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart.

Cardiovascular research - 1 May 2006

Valverde Carlos A, Mundiña-Weilenmann Cecilia, Reyes Mariano, Kranias Evangelia G, Escobar Ariel L, Mattiazzi Alicia

Abstract excerpt

OBJECTIVE: To investigate the importance of the phosphorylation of Ser16 and Thr17 sites of phospholamban (PLN) on intracellular Ca2+ (Cai2+) handling and contractile recovery of the stunned myocardium. METHODS: Cai2+ (Rhod-2, pulsed local-field fluorescence microscopy) and contractility (isovolumic left ventricular developed pressure, LVDP) were simultaneously measured in Langendorff perfused hearts from...

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PMID: 16516179
DOI: 10.1016/j.cardiores.2006.01.018

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PLN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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