Article
Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias.
Journal of molecular and cellular cardiology - 1 Dec 2011
Said M, Becerra R, Valverde C A, Kaetzel M A, Dedman J R, Mundiña-Weilenmann C, Wehrens X H, Vittone L, Mattiazzi A
Abstract excerpt
To explore whether CaMKII-dependent phosphorylation events mediate reperfusion arrhythmias, Langendorff perfused hearts were submitted to global ischemia/reperfusion. Epicardial monophasic or transmembrane action potentials and contractility were recorded. In rat hearts, reperfusion significantly...
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