Article
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis.
Nature - 31 Oct 2002
Petersen Petur H, Zou Kaiyong, Hwang Joseph K, Jan Yuh Nung, Zhong Weimin
Abstract excerpt
Neurons in most regions of the mammalian nervous system are generated over an extended period of time during development. Maintaining sufficient numbers of progenitors over the course of neurogenesis is essential to ensure that neural cells are produced in correct numbers and diverse types. The underlying molecular mechanisms, like those governing stem-cell self-renewal in general, remain poorly understood. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
