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Article

Expression patterns and novel splicing variants of glutathione-S-transferase isoenzymes of human lung and hepatocyte cell lines.

Cell and tissue research - 1 Jun 2006

Bauer Mario, Herbarth Olf, Aust Gabriela, Hengstler Jan G, Dotzauer Anja, Graebsch Carolin, Schmuecking Eike

Abstract excerpt

Polymorphic glutathione S-transferase (GST) enzymes are involved in the metabolism of xenobiotics. They are of particular interest when studying disease susceptibility and adverse drug responses. The present work deals with the genetic polymorphisms and expression of the five GST classes (alpha, mu, pi, theta and zeta) in human lung and hepatocyte cell lines. We have determined their bioavailability for in vitro...

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Source

Identifiers

PMID: 16501997
DOI: 10.1007/s00441-005-0150-8

Genes

GSTP1
GSTM1
GSTT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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