Article
Glutathione S-transferases: an overview in cancer research.
Expert opinion on drug metabolism & toxicology - 1 Feb 2010
Di Pietro Giuliano, Magno Luiz Alexandre V, Rios-Santos Fabrício
Abstract excerpt
IMPORTANCE OF THE FIELD: The Glutathione S-transferases (GSTs) have advanced beyond the classic view of their role in metabolism and are encouraging scientists to assess new approaches to cancer risk characterization and chemotherapy resistance and are opening up exciting possibilities in drug discovery. AREAS COVERED IN THIS REVIEW: In this review, the most recent knowledge about the impact of GST genetic...
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