Article
Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes.
International journal of hygiene and environmental health - 1 Jun 2003
Thier Ricarda, Brüning Thomas, Roos Peter H, Rihs Hans-Peter, Golka Klaus, Ko Yon, Bolt Hermann M
Abstract excerpt
Inherited genetic traits co-determine the susceptibility of an individual to a toxic chemical. Special emphasis has been put on individual responses to environmental and industrial carcinogens, but other chronic diseases are of increasing interest. Polymorphisms of relevant xenobiotic metabolising enzymes may be used as toxicological susceptibility markers. A growing number of genes encoding enzymes involved in...
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