Article
Evidence for increased cytochrome P450 1A1 expression in blood lymphocytes of lung cancer patients.
Mutation research - 2 Nov 2009
Shah Parag P, Saurabh Kumar, Pant Mohan C, Mathur Neeraj, Parmar Devendra
Abstract excerpt
To develop blood lymphocyte cytochrome P450 1A1 (CYP1A1) expression as a surrogate for monitoring tissue expression for polycyclic aromatic hydrocarbon (PAH) induced toxicity, the present study attempted to characterize CYP1A1 mRNA expression and its associated catalytic activity in freshly prepared blood lymphocytes isolated from healthy controls and patients suffering from tobacco induced lung cancer. Human...
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