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Article

Glutathione s-transferase p1: gene sequence variation and functional genomic studies.

Cancer research - 15 Jun 2008

Moyer Ann M, Salavaggione Oreste E, Wu Tse-Yu, Moon Irene, Eckloff Bruce W, Hildebrandt Michelle A T, Schaid Daniel J, Wieben Eric D, Weinshilboum Richard M

Abstract excerpt

Glutathione S-transferase P1 (GSTP1) is of importance for cancer research because of its role in detoxifying carcinogens, activating antineoplastic prodrugs, metabolizing chemotherapeutic agents, and its involvement in cell cycle and apoptosis regulation. Two common GSTP1 genetic polymorphisms have been studied extensively. However, the full range of GSTP1 genetic variation has not been systematically...

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Identifiers

PMID: 18559526
DOI: 10.1158/0008-5472.CAN-07-6724
PMCID: PMC2490824

Genes

GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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