Article
Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma.
Cancer letters - 15 Jan 1997
El-Zein R A, Zwischenberger J B, Abdel-Rahman S Z, Sankar A B, Au W W
Abstract excerpt
The relationship between genetic predisposition and development of specific cancers has not been adequately elucidated. In this study, the involvement of three polymorphic genes (CYP2E1, GSTM1, and GSTT1) in the development of different histological types of lung cancer was investigated. DNA was extracted from peripheral blood lymphocytes of lung cancer patients who have been long-term cigarette smokers (n = 52)....
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