Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma.

doi:10.1016/S0304-3835(96)04547-8

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Article

Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma.

Cancer letters - 15 Jan 1997

El-Zein R A, Zwischenberger J B, Abdel-Rahman S Z, Sankar A B, Au W W

Abstract excerpt

The relationship between genetic predisposition and development of specific cancers has not been adequately elucidated. In this study, the involvement of three polymorphic genes (CYP2E1, GSTM1, and GSTT1) in the development of different histological types of lung cancer was investigated. DNA was...

Topics

Adenocarcinoma
Adult
Aged
Cytochrome P-450 CYP2E1
Disease Susceptibility
Genotype
Glutathione Transferase
Humans
Lung Neoplasms
Middle Aged
Polymorphism, Genetic

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