Significance of genetic polymorphisms in glutathione S-transferase multigene family and lung cancer risk.

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Article

Significance of genetic polymorphisms in glutathione S-transferase multigene family and lung cancer risk.

International journal of occupational medicine and environmental health - 1 Jan 2001

Reszka E, Wasowicz W

Abstract excerpt

A vast number of studies are focused on investigating genetic polymorphism in order to estimate genetic contribution to the development of cancer. Possible cancer susceptibility genes have been sought among oncogenes, tumor suppressor genes, DNA repair genes and genes encoding phase I and phase II enzymes. Large individual differences in the biotransformation of xenobiotics have been explained on the basis of...

Topics

DNA Adducts
Gene Deletion
Genetic Predisposition to Disease
Glutathione S-Transferase pi
Glutathione Transferase
Isoenzymes
Lung Neoplasms
Occupational Diseases
Polymorphism, Genetic
Polymorphism, Single Nucleotide
Risk Factors
Smoking

Source

Open in PubMed

Identifiers

PMID: 11548073

Genes

GSTM1
GSTM3
GSTT1
GSTZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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