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Article

The portability of tagSNPs across populations: a worldwide survey.

Genome research - 1 Mar 2006

González-Neira Anna, Ke Xiayi, Lao Oscar, Calafell Francesc, Navarro Arcadi, Comas David, Cann Howard, Bumpstead Suzannah, Ghori Jilur, Hunt Sarah, Deloukas Panos, Dunham Ian, Cardon Lon R, Bertranpetit Jaume

Abstract excerpt

In the search for common genetic variants that contribute to prevalent human diseases, patterns of linkage disequilibrium (LD) among linked markers should be considered when selecting SNPs. Genotyping efficiency can be increased by choosing tagging SNPs (tagSNPs) in LD with other SNPs. However, it remains to be seen whether tagSNPs defined in one population efficiently capture LD in other populations; that is,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16467560
DOI: 10.1101/gr.4138406
PMCID: PMC1415211

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