Article
An evaluation of the performance of HapMap SNP data in a Shanghai Chinese population: analyses of allele frequency, linkage disequilibrium pattern and tagging SNPs transferability on chromosome 1q21-q25.
BMC genetics - 27 Feb 2008
Hu Cheng, Jia Weiping, Zhang Weihua, Wang Congrong, Zhang Rong, Wang Jie, Ma Xiaojing, Xiang Kunsan
Abstract excerpt
BACKGROUND: The HapMap project aimed to catalog millions of common single nucleotide polymorphisms (SNPs) in the human genome in four major populations, in order to facilitate association studies of complex diseases. To examine the transferability of Han Chinese in Beijing HapMap data to the Southern Han Chinese in Shanghai, we performed comparative analyses between genotypes from over 4,500 SNPs in a 21 Mb...
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