Article
A novel statistical algorithm for enhancing the utility of HapMap data to design genomic association studies in non-HapMap populations.
International journal of data mining and bioinformatics - 1 Jan 2011
Sarkar-Roy Neeta, Mondal Debabrata, Bhattacharya Paramita, Majumder Partha
Abstract excerpt
The HapMap database should be effectively used in designing disease association studies in non-HapMap populations. The efficiency of portability of tagSNPs from HapMap to non-HapMap populations is widely variable. A new algorithm is proposed for selecting SNPs from HapMap for use in non-HapMap populations by simultaneously considering and combining data on allele frequencies and linkage-disequilibrium values in...
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