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Article

HapMap tagSNP transferability in multiple populations: general guidelines.

Genomics - 1 Jul 2008

Xing Jinchuan, Witherspoon David J, Watkins W Scott, Zhang Yuhua, Tolpinrud Whitney, Jorde Lynn B

Abstract excerpt

Linkage disequilibrium (LD) has received much attention recently because of its value in localizing disease-causing genes. Due to the extensive LD between neighboring loci in the human genome, it is believed that a subset of the single nucleotide polymorphisms in a region (tagSNPs) can be selected to capture most of the remaining SNP variants. In this study, we examined LD patterns and HapMap tagSNP...

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Topics

Animals
Chromosome Mapping
Gene Frequency
Genetic Diseases, Inborn
Genome, Human
Human Genome Project
Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Linkage Disequilibrium

Polymorphism, Single Nucleotide

Racial Groups

Source

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Identifiers

PMID: 18482828
DOI: 10.1016/j.ygeno.2008.03.011
PMCID: PMC2471876

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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