Article
Portability of tag SNPs across isolated population groups: an example from India.
Annals of human genetics - 1 Jan 2008
Sarkar Roy N, Farheen S, Roy N, Sengupta S, Majumder P P
Abstract excerpt
Isolated population groups are useful in conducting association studies of complex diseases to avoid various pitfalls, including those arising from population stratification. Since DNA resequencing is expensive, it is recommended that genotyping be carried out at tagSNP (tSNP) loci. For this, tSNPs identified in one isolated population need to be used in another. Unless tSNPs are highly portable across...
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