Article
Significant variation in haplotype block structure but conservation in tagSNP patterns among global populations.
European journal of human genetics : EJHG - 1 Mar 2007
Gu Sheng, Pakstis Andrew J, Li Hui, Speed William C, Kidd Judith R, Kidd Kenneth K
Abstract excerpt
The initial belief that haplotype block boundaries and haplotypes were largely shared across populations was a foundation for constructing a haplotype map of the human genome using common SNP markers. The HapMap data document the generality of a block-like pattern of linkage disequilibrium (LD) with regions of low and high haplotype diversity but differences among the populations. Studies of many additional...
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