Article
HBeAg negative variants and their role in the natural history of chronic hepatitis B virus infection.
World journal of gastroenterology - 28 Jun 2014
Alexopoulou Alexandra, Karayiannis Peter
Abstract excerpt
Molecular virology methods including polymerase chain reaction, cloning and sequencing have revolutionised our understanding of viral genome variation. In the case of hepatitis B virus (HBV), sequencing studies have identified a number of virus variants normally found during the natural course of chronic infection. The appearance of the precore stop codon (with G-for-A substitution at position 1896) and basal...
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