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[Assessment of the presence of mutations of the epidermal growth factor receptors in tumors of various histologies].

I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] - 1 Jan 2000

Leone A, Pisa R, Gasbarra R, Costanzi-Porrini S, Cavazzana A, Bevilacqua G, Graziano P, Remotti D, Valle M, Garofalo A

Abstract excerpt

Recent reports from US and Japan have established that mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (Egfr) occur in a subset of patients with lung cancer that respond to therapy with gefitinib, a TK inhibitor. To gain further insights into the role of Egfr in carcinogenesis of lung and tumors of diverse histology, that are currently under investigation with drugs of the...

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PMID: 16437988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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