Article
[Epidermal growth factor receptor mutation in non-small cell lung cancer and breast cancer].
Yi chuan = Hereditas - 1 May 2007
Zhao Ya-Li, Li Qi, Li Xiang-Hong, Han Wei-Dong, Hao Hao-Jie, Si Yi-Ling, Wu Zhi-Qiang
Abstract excerpt
Somatic mutation in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR) gene is associated with the sensitivity of non-smal cell lung cancer (NSCLC) to TK inhibitor Gefitinib. Mutational analysis for EGFR exons 19 and 21 was performed in 75 NSCLC and 10 breast cancer pa...
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