Article
Methods for the selection of tagging SNPs: a comparison of tagging efficiency and performance.
European journal of human genetics : EJHG - 1 Feb 2007
Ding Keyue, Kullo Iftikhar J
Abstract excerpt
There is great interest in the use of tagging single nucleotide polymorphisms (tSNPs) to facilitate association studies of complex diseases. This is based on the premise that a minimum set of tSNPs may be sufficient to capture most of the variation in certain regions of the human genome. Several...
Topics
- Chromosome Mapping
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Linkage Disequilibrium
- Polymorphism, Single Nucleotide
- Reproducibility of Results
- Sensitivity and Specificity
- Sequence Tagged Sites
- White People