Article
Methods for the selection of tagging SNPs: a comparison of tagging efficiency and performance.
European journal of human genetics : EJHG - 1 Feb 2007
Ding Keyue, Kullo Iftikhar J
Abstract excerpt
There is great interest in the use of tagging single nucleotide polymorphisms (tSNPs) to facilitate association studies of complex diseases. This is based on the premise that a minimum set of tSNPs may be sufficient to capture most of the variation in certain regions of the human genome. Several methods have been described to select tSNPs, based on either haplotype-block structure or independent of the underlying...
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