Article
Effectiveness of in silico tagSNP selection methods: virtual analysis of the genotypes of pharmacogenetic genes.
Pharmacogenomics - 1 Oct 2007
Nam Myung-Hyun, Won Hong-Hee, Lee Kyung-A, Kim Jong-Won
Abstract excerpt
INTRODUCTION: SNP tagging has been recently introduced, and the use of this strategy reduces the dimension of disease association studies and eventually saves on genotyping costs. There is no single set of tagging SNPs (tagSNPs) that will satisfy every association study design; thus, many different methods have been introduced. We evaluated various tagSNP selection methods using known haplotype data of...
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