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Article

An efficient comprehensive search algorithm for tagSNP selection using linkage disequilibrium criteria.

Bioinformatics (Oxford, England) - 15 Jan 2006

Qin Zhaohui S, Gopalakrishnan Shyam, Abecasis Gonçalo R

Abstract excerpt

MOTIVATION: Selecting SNP markers for genome-wide association studies is an important and challenging task. The goal is to minimize the number of markers selected for genotyping in a particular platform and therefore reduce genotyping cost while simultaneously maximizing the information content provided by selected markers. RESULTS: We devised an improved algorithm for tagSNP selection using the pairwise r(2)...

Topics

Algorithms
Artificial Intelligence
Base Sequence
Chromosome Mapping
Expressed Sequence Tags
Genetic Markers
Linkage Disequilibrium
Molecular Sequence Data
Pattern Recognition, Automated
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Alignment

Sequence Analysis, DNA

Software

Source

Identifiers

PMID: 16269414
DOI: 10.1093/bioinformatics/bti762

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