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Article

Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta.

Molecular and cellular biology - 1 Apr 2006

Budd Martin E, Reis Clara C, Smith Stephanie, Myung Kyungjae, Campbell Judith L

Abstract excerpt

The precise machineries required for two aspects of eukaryotic DNA replication, Okazaki fragment processing (OFP) and telomere maintenance, are poorly understood. In this work, we present evidence that Saccharomyces cerevisiae Pif1 helicase plays a wider role in DNA replication than previously appreciated and that it likely functions in conjunction with Dna2 helicase/nuclease as a component of the OFP machinery....

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Source

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Identifiers

PMID: 16537895
DOI: 10.1128/MCB.26.7.2490-2500.2006
PMCID: PMC1430326

Genes

PIF1
DNA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta.PMID 16537895Read ↗

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