Article
Mannose-binding lectin: structure, function, genetics and disease associations.
Reviews in immunogenetics - 1 Jan 2000
Turner M W, Hamvas R M
Abstract excerpt
Mannose-binding lectin (MBL), a serum protein characterised by both collagenous regions and lectin domains, plays an important role in innate immune defence. It binds to the repeating sugar arrays on many microbial surfaces through multiple lectin domains and, following binding, is able to activate the complement system via an associated serum protease, MASP-2. Serum levels of MBL are influenced by three...
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