Article
Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives.
PloS one - 1 Jan 2014
Goeldner Isabela, Skare Thelma L, Utiyama Shirley R, Nisihara Renato M, Tong Hoang van, Messias-Reason Iara J T, Velavan Thirumalaisamy P
Abstract excerpt
INTRODUCTION: Rheumatoid arthritis (RA) is a commonly occurring systemic inflammatory auto immune disease and is believed to be associated with genetic factors. The innate immune complement protein Mannose binding lectin (MBL) and their MBL2 genetic variants are associated with different infectious and autoimmune diseases. METHODS: In a Brazilian cohort, we aim to associate the functional role of circulating MBL...
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