Article
Mannan-binding lectin deficiency - Good news, bad news, doesn't matter?
Clinical immunology (Orlando, Fla.) - 1 Apr 2012
Heitzeneder Sabine, Seidel Markus, Förster-Waldl Elisabeth, Heitger Andreas
Abstract excerpt
Mannan-binding lectin (MBL) deficiency has been classified as a commonly occurring immune disorder, affecting approximately 30% of the human population. MBL, being part of the innate immune system, supports the recognition of infectious pathogens by binding to carbohydrate moieties expressed on microorganisms and activates the lectin pathway of the complement system. MBL2 gene polymorphisms are associated with...
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