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Article

Mannose-binding lectin deficiency--revisited.

Molecular immunology - 1 Sept 2003

Garred Peter, Larsen Flemming, Madsen Hans O, Koch Claus

Abstract excerpt

There is an emerging interest for mannose-binding lectin (MBL) due to its role in innate immunity. In this survey we present a mixture of old and new data describing the effect MBL polymorphisms may have on the level and function of the molecule. Three single nucleotide substitutions in exon 1 of the mbl2 gene cause a dominant decrease of functional MBL in the circulation. Additionally, promoter variants...

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PMID: 12914814
DOI: 10.1016/s0161-5890(03)00104-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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