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Mannan-binding lectin: clinical significance and applications.

Biochimica et biophysica acta - 19 Sept 2002

Kilpatrick David C

Abstract excerpt

Mannan-binding lectin (MBL) is a collectin (protein with both collagen-like and C-type lectin domains) synthesised in the liver and secreted into the bloodstream. Its plasma concentration is for the most part genetically determined by a series of allelic dimorphisms located both in the structural gene and in the promoter region. Genotypes made up of combinations of seven haplotypes are mainly responsible for a...

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PMID: 12223282
DOI: 10.1016/s0304-4165(02)00321-5

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