Article
Apolipoprotein E genotype does not influence rates of cognitive decline in Alzheimer's disease.
Neurology - 1 Aug 1996
Growdon J H, Locascio J J, Corkin S, Gomez-Isla T, Hyman B T
Abstract excerpt
BACKGROUND: Inheritance of the apolipoprotein E (apoE) epsilon 4 allele is a risk factor for developing Alzheimer's disease (AD) and is associated with a lower age of dementia onset. The purpose of this study was to determine whether apoE genotypes differentially influence the course of cognitive decline in AD dementia. METHODS: We administered nine cognitive tests that assessed explicit memory, attention,...
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