Article
Cognitive Decline in Alzheimer's Disease Is Not Associated with APOE.
Journal of Alzheimer's disease : JAD - 1 Jan 2021
Katzourou Ioanna, Leonenko Ganna, Ivanov Dobril, Meggy Alun, Marshall Rachel, Sims Rebecca, Williams Julie, Holmans Peter, Escott-Price Valentina
Abstract excerpt
BACKGROUND: The rate of cognitive decline in Alzheimer's disease (AD) has been found to vary widely between individuals, with numerous factors driving this heterogeneity. OBJECTIVE: This study aimed to compute a measure of cognitive decline in patients with AD based on clinical information and to utilize this measure to explore the genetic architecture of cognitive decline in AD. METHODS: An in-house cohort of...
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