Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Covariability of selected amino acid positions for HIV type 1 subtypes C and B.

AIDS research and human retroviruses - 1 Dec 2005

Gilbert Peter B, Novitsky Vladimir, Essex Max

Abstract excerpt

We studied covariability of selected amino acid positions in globally dominant HIV-1 subtype C viruses. The analyzed sequences spanned the V3 loop, Gag p17, Gag p24, and five CTL epitope-rich regions in Gag, Nef, and Tat. The corresponding regions in HIV-1 subtype B were also evaluated. The analyses identified a great number of covarying pairs and triples of sites in the HIV-1B V3 loop (173 site pairs, 242 site...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Products, tat
Share to Gene Products, gag
Share to Gene Products, nef

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to Immunodominant Epitopes

Share to nef Gene Products, Human Immunodeficiency Virus

Share to Statistics, Nonparametric

Share to tat Gene Products, Human Immunodeficiency Virus

Source

Identifiers

PMID: 16379605
DOI: 10.1089/aid.2005.21.1016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Covariability of selected amino acid positions for HIV type 1 subtypes C and B.PMID 16379605Read ↗

Covariation of mutations in the V3 loop of human immunodeficiency virus type 1 envelope protein: an information theoretic analysis.Semantic proximity Read ↗

Detecting and understanding genetic and structural features in HIV-1 B subtype V3 underlying HIV-1 co-receptor usage.Semantic proximity Read ↗

Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.Semantic proximity Read ↗

HIV-1 subtype B protease and reverse transcriptase amino acid covariation.Semantic proximity Read ↗

Integrated analysis of residue coevolution and protein structures capture key protein sectors in HIV-1 proteins.Semantic proximity Read ↗

Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics.Semantic proximity Read ↗

Selected amino acid mutations in HIV-1 B subtype gp41 are Associated with Specific gp120V3signatures in the regulation of Co-Receptor usageSemantic proximity Read ↗

Complex positive selection pressures drive the evolution of HIV-1 with different co-receptor tropisms.Semantic proximity Read ↗

Co-operative additive effects between HLA alleles in control of HIV-1.Semantic proximity Read ↗

Novel nucleotide and amino acid covariation between the 5'UTR and the NS2/NS3 proteins of hepatitis C virus: bioinformatic and functional analyses.Semantic proximity Read ↗

Impact of HLA class I functional divergence on HIV control.Semantic proximity Read ↗

On the Physicochemical and Structural Modifications Associated with HIV-1 Subtype B Tropism Transition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.