Article
The class II phosphoinositide 3-kinase C2beta is not essential for epidermal differentiation.
Molecular and cellular biology - 1 Dec 2005
Harada Kazutoshi, Truong Amy B, Cai Ti, Khavari Paul A
Abstract excerpt
Phosphoinositide 3-kinases (PI3Ks) regulate an array of cellular processes and are comprised of three classes. Class I PI3Ks include the well-studied agonist-sensitive p110 isoforms; however, the functions of class II and III PI3Ks are less well characterized. Of the three class II PI3Ks, C2alpha and C2beta are widely expressed in many tissues, including the epidermis, while C2gamma is confined to the liver. In...
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