Article
Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling.
Molecular and cellular biology - 1 Oct 2003
Takenaka Kei, Fukami Kiyoko, Otsuki Makiko, Nakamura Yoshikazu, Kataoka Yuki, Wada Mika, Tsuji Kohichiro, Nishikawa Shin-Ichi, Yoshida Nobuaki, Takenawa Tadaomi
Abstract excerpt
Phospholipase C (PLC) plays important roles in phosphoinositide turnover by regulating the calcium-protein kinase C signaling pathway. PLC-L2 is a novel PLC-like protein which lacks PLC activity, although it is very homologous with PLC delta. PLC-L2 is expressed in hematopoietic cells, but its ph...
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