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Article

Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling.

Molecular and cellular biology - 1 Oct 2003

Takenaka Kei, Fukami Kiyoko, Otsuki Makiko, Nakamura Yoshikazu, Kataoka Yuki, Wada Mika, Tsuji Kohichiro, Nishikawa Shin-Ichi, Yoshida Nobuaki, Takenawa Tadaomi

Abstract excerpt

Phospholipase C (PLC) plays important roles in phosphoinositide turnover by regulating the calcium-protein kinase C signaling pathway. PLC-L2 is a novel PLC-like protein which lacks PLC activity, although it is very homologous with PLC delta. PLC-L2 is expressed in hematopoietic cells, but its physiological roles and intracellular functions in the immune system have not yet been clarified. To elucidate the...

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Identifiers

PMID: 14517301
DOI: 10.1128/MCB.23.20.7329-7338.2003
PMCID: PMC230318

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BCR

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Source receipt: pubmed, retrieved 7 Sept 2026.

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